Blastocyst Culture

Who is this for?

Blastocyst culture may be suitable for patients who have good quality embryos on day two or three or who are considering having a single good quality embryo replaced.

What does this treatment involve?

A blastocyst is an embryo that has been allowed to develop in the laboratory for five or six days after egg collection. This is in contrast to standard IVF where embryos are only allowed to develop up to day two or three in the laboratory, before being transferred to the uterus.

Blastocyst culture may be suitable for patients who have good quality embryos on day two or three or who are considering having a single good quality embryo replaced. Embryos which become blastocysts have a higher chance of implantation than embryos on day two or three. Blastocyst transfer is also more physiological as it mimics natural conception.

This creates a perfect partnership between the embryo and the uterine lining, aiding the implantation process. Unfortunately, not all embryos created in the laboratory can develop and survive for five days. It is therefore important that we select patients who on day three have a minimum number of good quality embryos. If the number of embryos is low, there may be no significant advantage to leaving the embryos in the laboratory and you will be advised to have embryos replaced earlier to avoid the risk of there being no blastocysts to transfer.